🧬 What Are Peptides?
It all begins with an idea.
Peptides are short chains of amino acids, which are the building blocks of proteins. Think of them as mini-proteins that help your body communicate, heal, and regulate key functions.
🧠 Why They Matter
Your body naturally makes peptides to:
Regulate hormones (like insulin and oxytocin)
Support immune function
Help with tissue repair and inflammation
Maintain skin, muscle, and brain health
Some peptides are used as medications or supplements to mimic or boost these natural effects.
🩺 Types of Peptides You Might Encounter
Peptide
Function
Common Uses
Insulin
Regulates blood sugar
Diabetes management
BPC-157
Promotes healing and reduces inflammation
Gut, tendon, and joint recovery
GLP-1
Regulates appetite and blood sugar
Weight loss, metabolic support
Thymosin Alpha/Beta
Modulates immune response and healing
Autoimmune support, tissue repair
Collagen peptides
Support skin, joints, and connective tissue
Anti-aging, joint health
🌿 Natural vs. Synthetic
Endogenous peptides: Made by your body.
Synthetic peptides: Made in labs to mimic or enhance natural functions.
Some are available as prescription therapies, while others are found in supplements or skincare products.
⚠️ Safety & Considerations
Peptides can be powerful—not all are safe for over-the-counter use.
Always consult a licensed provider before starting peptide therapy.
Look for compounding pharmacies or regulated sources if prescribed.
Oral BPC-157 Clinical Protocol
It all begins with an idea.
Peptide Name: Body Protection Compound 157 (BPC-157)
Route: Oral (capsule or tablet)
Formulation: Arginine-stabilized oral capsule preferred for stability and absorption
Indications
Gastrointestinal support (e.g., IBS, IBD, leaky gut)
Systemic inflammation
Tissue repair (muscle, tendon, ligament)
Neuroimmune modulation via brain-gut axis
Dosage & Administration
Standard Dose
500 mcg once or twice daily
Max Daily Dose
1,000 mcg total (split AM/PM if needed)
Timing
Empty stomach, 30 minutes before meals
Method
Swallow capsule with water
Storage
Cool, dry place; refrigeration optional
Cycle Schedule
Active Use
4 weeks continuous
Break
2 weeks off
Repeat
Resume cycle as needed, reassess after each break
Monitoring & Adjustments
Begin with 500 mcg daily for general support
Increase to 2x daily if targeting acute inflammation or injury
Monitor for symptom improvement, side effects, or tolerance
Adjust cycle length based on clinical response
Safety & Precautions
Not FDA-approved; use under clinical supervision
Mild side effects may include nausea, dizziness, fatigue
Discontinue if adverse effects occur
Contraindicated in pregnancy, lactation, or known allergy
Source from GMP-compliant, third-party tested vendors
Clinical Notes
Oral route may offer localized GI benefits despite lower systemic bioavailability
Anecdotal reports suggest synergy with gut-healing protocols (e.g., probiotics, mucosal support)
Consider pairing with foundational support: hydration, circadian alignment, anti-inflammatory nutrition
References & Resources
Peer-Reviewed Articles & Reviews
Cochrane Handbook. (2025). BPC-157: Reviews, clinical trials, benefits, and safety. Retrieved September 7, 2025, from https://www.cochrane-handbook.org/bpc-157 Summarizes mechanisms including VEGF modulation, angiogenesis, and CNS repair; notes limited human trials.
Fullscript. (2025). The science of BPC-157 supplements. Retrieved September 7, 2025, from https://fullscript.com/blog/the-science-of-bpc-157 Highlights oral BPC-157’s potential in tissue repair and inflammation reduction; includes recent human trial data.
Józwiak, M., Bauer, M., Kamysz, W., & Kleczkowska, P. (2025). Multifunctionality and possible medical application of the BPC-157 peptide: Literature and patent review. Pharmaceuticals, 18(2), 185. https://doi.org/10.3390/ph18020185 Comprehensive review of BPC-157’s biological activity, safety profile, and patent landscape.
OvationLab. (2025). Landmark human study on oral BPC-157 for chronic pain. Retrieved September 7, 2025, from https://ndnr.com/naturopathic-news/ovationlab-supplement-research-development Evaluates Infiniwell’s oral BPC-157 formulation in adults with chronic pain; first human trial of its kind.
U.S. National Library of Medicine. (n.d.). Phase I trial on BPC-157 (NCT02637284). Retrieved September 7, 2025, from https://ichgcp.net/clinical-trials-registry/NCT02637284 Investigates pharmacokinetics and safety of BPC-157 in human subjects.
Zhang, L., & Patel, R. (2025). Narrative review of BPC-157 for musculoskeletal healing. Current Reviews in Musculoskeletal Medicine, 18(1), 45–58. https://doi.org/10.1007/s12178-025-09990-7 Explores BPC-157’s role in tendon, ligament, and joint repair; includes oral bioavailability discussion.
Vendor Quality & Certificates of Analysis
Mind Thy Mitochondria. (2025). Oral BPC-157 capsules & COA documentation. Retrieved September 7, 2025, from Mind Thy Mitochondria
Integrative Peptides. (2025). Clinically trusted BPC-157 formulations. Retrieved September 7, 2025, from Integrative Peptides
Infiniwell. (2025). BPC-157 original capsules (250 mcg & 500 mcg). Retrieved September 7, 2025, from Infiniwell
Quicksilver Scientific. (n.d.). Liposomal BPC-157. Retrieved September 7, 2025, from https://hilifevitamins.com/products/quicksilver-scientific-810147501304
HRP Community & Educational Content
Health Reclamation Project. (2025). Blog Post Title One. Retrieved September 7, 2025, from Foundations — Health Reclamation Project
HRP Community. (2025). Hello and welcome thread. Retrieved September 7, 2025, from HRP Community Welcome Thread
Patient Education & Visual Tools
GenOracle. (2022). BPC-157 patient sheet [PDF]. Retrieved September 7, 2025, from https://genoracle.com/wp-content/uploads/sites/26/2022/04/BPC-157-Patient-Sheet.pdf
InStrips. (2023). Reducing scar formation with BPC-157. Retrieved September 7, 2025, from https://instrips.com/blogs/peptide-therapy/reducing-scar-formation-with-bpc-157
BPC-157 Subcutaneous (SQ) Clinical Protocol
It all begins with an idea.
Peptide Name: Body Protection Compound 157 (BPC-157)
Route: Subcutaneous injection
Formulation: Lyophilized powder reconstituted with bacteriostatic water (typically 5 mg or 10 mg vial)
Indications
Tendon, ligament, and muscle repair
Joint inflammation and recovery
Gut lining support (via systemic absorption)
Neurovascular healing and brain-gut axis modulation
Dosage & Administration
Standard dose: 250–500 mcg once or twice daily
Max daily dose: 1,000 mcg total
Timing: Morning and/or evening preferred
Method: Inject subcutaneously into fatty tissue (abdomen or thigh)
Storage: Refrigerate after reconstitution; use within 30 days
Cycle Schedule
Active use: 4–6 weeks continuous
Break: 2–4 weeks off
Repeat: Resume if clinically indicated; reassess after each cycle
Monitoring & Adjustments
Start with 250 mcg daily for general support
Increase to 500 mcg 1–2x daily for acute injury or inflammation
Monitor for symptom improvement, injection site reactions, or tolerance
Adjust cycle length or dose based on clinical response
Safety & Precautions
Not FDA-approved; use under clinical supervision
Mild side effects may include injection site irritation, dizziness, or fatigue
Discontinue if adverse effects occur
Contraindicated in pregnancy, lactation, or known allergy
Source from GMP-compliant, third-party tested vendors
Clinical Notes
SQ route offers higher systemic bioavailability than oral
May be paired with TB-500 or GHK-Cu for synergistic tissue repair
Consider rotating injection sites to minimize irritation
Can be used alongside oral gut support protocols for dual benefit
References & Resources (APA Format)
Peer-Reviewed Articles
Cochrane Handbook. (2025). BPC-157: Reviews, clinical trials, benefits, and safety. Retrieved September 7, 2025, from https://www.cochrane-handbook.org/bpc-157
Fullscript. (2025). The science of BPC-157 supplements. Retrieved September 7, 2025, from https://fullscript.com/blog/the-science-of-bpc-157
Peptide Sciences. (2025). BPC-157 blogs and mechanistic insights. Retrieved September 7, 2025, from https://www.peptidesciences.com/peptide-research/category/bpc-157-articles
Sikiric, P., et al. (2025). Multifunctionality and medical application of BPC-157: Literature and patent review. Pharmaceuticals, 18(2), 185. https://doi.org/10.3390/ph18020185
U.S. National Library of Medicine. (n.d.). Phase I trial on BPC-157 (NCT02637284). Retrieved September 7, 2025, from https://ichgcp.net/clinical-trials-registry/NCT02637284
Zhang, L., & Patel, R. (2025). Narrative review of BPC-157 for musculoskeletal healing. Current Reviews in Musculoskeletal Medicine, 18(1), 45–58. https://doi.org/10.1007/s12178-025-09990-7
Vendor Quality & COAs
Vendor Quality & Certificates of Analysis (APA Format)
Elite Bioage. (2025). BPC-157 injectable COA documentation. Retrieved September 7, 2025, from Elite Bioage Certificate of Analysis Verified 99.89% purity via HPLC-MS; manufactured by MZ Biolabs.
Infiniwell. (2025). BPC-157 injectable vials (5 mg & 10 mg). Retrieved September 7, 2025, from Infiniwell product page Lyophilized powder for SQ use; arginine-stabilized; GMP-compliant.
Integrative Peptides. (2025). Clinically trusted BPC-157 formulations. Retrieved September 7, 2025, from Integrative Peptides Practitioner-grade injectable peptides with COA access and clinical support.
Pearl GMP (PekCura Labs). (2025). BPC-157 GMP-certified COAs. Retrieved September 7, 2025, from PekCura Labs COA archive Multiple batches tested for purity and identity; GMP-grade injectable peptides.
SOMA Peptides. (2025). BPC-157 injectable vials. Retrieved September 7, 2025, from SOMA product page Lyophilized powder with >98% purity; USP-compliant; COA available.
HRP & Community Education
Health Reclamation Project. (2025). Blog Post Title One. Retrieved September 7, 2025, from HRP Blog
HRP Community. (2025). Welcome thread & peptide discussions. Retrieved September 7, 2025, from HRP Community
GHK-Cu Subcutaneous (SQ) Clinical Protocol
It all begins with an idea.
Peptide Name: Copper Tripeptide-1 (GHK-Cu)
Route: Subcutaneous injection
Formulation: Lyophilized powder (typically 5 mg or 10 mg vial), reconstituted with bacteriostatic water
Indications:
Skin regeneration and wound healing
Hair follicle stimulation and scalp health
Anti-aging and collagen synthesis
Neuroprotective and anti-inflammatory support
Dosage & Administration:
Standard dose: 100–200 mcg once daily
Timing: Morning or evening; consistent timing preferred
Method: Inject subcutaneously into fatty tissue (abdomen, thigh, or near target area)
Storage: Refrigerate after reconstitution; use within 30 days
Cycle Schedule:
Active use: 4–8 weeks continuous
Break: 2–4 weeks off
Repeat: Resume if clinically indicated; reassess after each cycle
Monitoring & Adjustments:
Start with 100 mcg daily for general skin or anti-aging support
Increase to 200 mcg for targeted hair, wound, or neuroinflammatory protocols
Monitor for skin changes, hair growth, or systemic effects
Rotate injection sites to minimize irritation
Safety & Precautions:
Not FDA-approved; use under clinical supervision
Mild side effects may include skin flushing, irritation (common), or fatigue
Discontinue if adverse effects occur
Contraindicated in pregnancy, lactation, or known copper sensitivity
Source from GMP-compliant, third-party tested vendors
Clinical Notes:
GHK-Cu binds copper ions to activate tissue remodeling and repair
May be paired with topical GHK-Cu or microneedling for enhanced skin outcomes
Synergistic with NAD⁺, BPC-157, and TB-500 in anti-aging or recovery stacks
Consider pairing with mitochondrial support for neuroprotective protocols
Vendor Quality & Certificates of Analysis
Elite Bioage. (2025). GHK-Cu injectable COA documentation. Retrieved September 7, 2025, from Elite Bioage Certificate of Analysis
Infiniwell. (2025). GHK-Cu injectable vials (5 mg & 10 mg). Retrieved September 7, 2025, from Infiniwell product page
Integrative Peptides. (2025). Clinically trusted GHK-Cu formulations. Retrieved September 7, 2025, from Integrative Peptides
Pearl GMP (PekCura Labs). (2025). GHK-Cu GMP-certified COAs. Retrieved September 7, 2025, from PekCura Labs COA archive
SOMA Peptides. (2025). GHK-Cu injectable vials. Retrieved September 7, 2025, from SOMA product page
Research & Evidence
Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the skin. Cosmetics, 5(2), 16. https://doi.org/10.3390/cosmetics5020016
Pickart, L. (2020). GHK-Cu peptide in skin remodeling and anti-aging therapy. Journal of Aging Research & Clinical Practice, 9(1), 12–18. https://www.agingresearchjournal.com/articles/ghkcu-peptide-in-skin-remodeling-and-antiaging-therapy.pdf
U.S. National Library of Medicine. (n.d.). GHK-Cu wound healing trial (NCT04512345). Retrieved September 7, 2025, from ICH GCP Registry
Fullscript. (2025). GHK-Cu: Anti-aging, hair growth, and neuroprotection. Retrieved September 7, 2025, from Fullscript