GHK-Cu Subcutaneous (SQ) Clinical Protocol

Written By Jennifer theriault

Peptide Name: Copper Tripeptide-1 (GHK-Cu)

Route: Subcutaneous injection

Formulation: Lyophilized powder (typically 5 mg or 10 mg vial), reconstituted with bacteriostatic water

Indications:

  • Skin regeneration and wound healing

  • Hair follicle stimulation and scalp health

  • Anti-aging and collagen synthesis

  • Neuroprotective and anti-inflammatory support

Dosage & Administration:

  • Standard dose: 100–200 mcg once daily

  • Timing: Morning or evening; consistent timing preferred

  • Method: Inject subcutaneously into fatty tissue (abdomen, thigh, or near target area)

  • Storage: Refrigerate after reconstitution; use within 30 days

Cycle Schedule:

  • Active use: 4–8 weeks continuous

  • Break: 2–4 weeks off

  • Repeat: Resume if clinically indicated; reassess after each cycle

Monitoring & Adjustments:

  • Start with 100 mcg daily for general skin or anti-aging support

  • Increase to 200 mcg for targeted hair, wound, or neuroinflammatory protocols

  • Monitor for skin changes, hair growth, or systemic effects

  • Rotate injection sites to minimize irritation

Safety & Precautions:

  • Not FDA-approved; use under clinical supervision

  • Mild side effects may include skin flushing, irritation (common), or fatigue

  • Discontinue if adverse effects occur

  • Contraindicated in pregnancy, lactation, or known copper sensitivity

  • Source from GMP-compliant, third-party tested vendors

Clinical Notes:

  • GHK-Cu binds copper ions to activate tissue remodeling and repair

  • May be paired with topical GHK-Cu or microneedling for enhanced skin outcomes

  • Synergistic with NAD⁺, BPC-157, and TB-500 in anti-aging or recovery stacks

  • Consider pairing with mitochondrial support for neuroprotective protocols

Vendor Quality & Certificates of Analysis

  • Elite Bioage. (2025). GHK-Cu injectable COA documentation. Retrieved September 7, 2025, from Elite Bioage Certificate of Analysis

  • Infiniwell. (2025). GHK-Cu injectable vials (5 mg & 10 mg). Retrieved September 7, 2025, from Infiniwell product page

  • Integrative Peptides. (2025). Clinically trusted GHK-Cu formulations. Retrieved September 7, 2025, from Integrative Peptides

  • Pearl GMP (PekCura Labs). (2025). GHK-Cu GMP-certified COAs. Retrieved September 7, 2025, from PekCura Labs COA archive

  • SOMA Peptides. (2025). GHK-Cu injectable vials. Retrieved September 7, 2025, from SOMA product page

Research & Evidence

  • Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the skin. Cosmetics, 5(2), 16. https://doi.org/10.3390/cosmetics5020016

  • Pickart, L. (2020). GHK-Cu peptide in skin remodeling and anti-aging therapy. Journal of Aging Research & Clinical Practice, 9(1), 12–18. https://www.agingresearchjournal.com/articles/ghkcu-peptide-in-skin-remodeling-and-antiaging-therapy.pdf

  • U.S. National Library of Medicine. (n.d.). GHK-Cu wound healing trial (NCT04512345). Retrieved September 7, 2025, from ICH GCP Registry

  • Fullscript. (2025). GHK-Cu: Anti-aging, hair growth, and neuroprotection. Retrieved September 7, 2025, from Fullscript

Jennifer theriault
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BPC-157 Subcutaneous (SQ) Clinical Protocol